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Dr Richard Wall

Assistant Professor

London School of Hygiene & Tropical Medicine
Keppel Street
London
WC1E 7HT
United Kingdom

Jump to: Affiliations Teaching Research Publications
Richard completed his PhD at the University of Nottingham before starting a research position in Prof Rita Tewari’s group working in a range of areas from parasite motility to cell division using the malaria model, Plasmodium berghei. He then moved to the University of Dundee to work on mode of action studies for new antiparasitic drugs in the group of Dr Susan Wyllie. This combined a myriad of genetic, proteomic and bioinformatic techniques to identify the target of new treatments against parasites that cause Chagas’ disease, Leishmaniasis, Sleeping Sickness and Malaria. Currently, he leads the lab of Prof Anil Koul at LSHTM with an aim to discover new drugs for the treatment of M. tuberculosis as well as investigating the underlying biology surrounding key drug targets.

Affiliations
Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Centres

TB Centre
Antimicrobial Resistance Centre

Teaching
Richard regularly supervises lab-based summer project students and is a personal tutor for the MSc Medical Microbiology course. He also leads the group tutorials and is an assessor for the Novel Drug Discovery & AMR (3169) MSc module.

Research
Richard's primary research objective is driving various TB drug discovery projects in close collaboration with our industry partner. His other interests include using saturation mutagenesis to identify resistance-conferring mutations, the impact of target overexpression in drug resistance and drug target deconvolution of phenotypic hit compounds.
Research Area
Bacteriology
Genetics
Microbiology
Molecular biology
Parasitology
Drug discovery and development
Disease and Health Conditions
Tuberculosis
Chagas disease
Leishmaniasis
African trypanosomiasis
Malaria

Selected Publications
Pérez, CA; Lenaerts, A; Villellas, C; Guillemont, J; Dallow, J; Painter, H; Ammerman, N; Hassan, A; Golovkine, G; Brock, L; Chauffour, A; Aubry, A; Mai, T; Wong, S; CLARK, T; Nam, K; Kim, J; Choi, J; Crabbe, M; Esqui, J; Lounis, N; Stoops, B; Amssoms, K; Bartolome-Nebreda, J; Gruppo, V; ... Lamprecht, D.
2024
Research Square
PHELAN, J; Van den Heede, K; Masyn, S; Verbeeck, R; Lamprecht, DA; KOUL, A; WALL, RJ;
2024
Scientific reports
Trenaman, A; Tinti, M; WALL, RJ; Horn, D;
2024
Nature communications
Lamprecht, D; WALL, R; Davies, C; Pearson, W; Davis, E; Willcocks, S; Dallow, J; Leemans, A; Wetzel, J; Daems, S; Sancheti, P; Monshouwer, M; Aguilar-Pérez, C; Koul, A; Sprangers, J; Fiogbe, P; Saylock, S; Ricketts, M; Huff, A; Grell, T; Draghia-Akli, R; Lin, S; Gerber, M; Dhar, N; Vos, A; ... Jackson, P.
2024
Research Square
WALL, RJ; MacGowan, SA; Hallyburton, I; Syed, AJ; Ajay Castro, S; Dey, G; Milne, R; Patterson, S; PHELAN, J; Wiedemar, N; Wyllie, S;
2024
mBio
Tulloch, LB; Tinti, M; WALL, RJ; Weidt, SK; Corpas-Lopez, V; Dey, G; Smith, TK; Fairlamb, AH; Barrett, MP; Wyllie, S;
2024
PLoS pathogens
Zhang, N; Samad, A; Zahedifard, F; WALL, R; Horn, D; Zoltner, M; Field, M;
2024
bioRxiv
Ngum, N; Aziz, M; WALL, R; Duce, I; Mellor, I;
2024
Authorea Preprints
Braillard, S; Keenan, M; Breese, KJ; Heppell, J; Abbott, M; Islam, R; Shackleford, DM; Katneni, K; Crighton, E; Chen, G; Patil, R; Lee, G; White, KL; Carvalho, S; WALL, RJ; Chemi, G; Zuccotto, F; González, S; Marco, M; Deakyne, J; Standing, D; Brunori, G; Lyon, JJ; Castañeda-Casado, P; Camino, I; ... Chatelain, E.
2023
Science translational medicine
González, S; WALL, RJ; Thomas, J; Braillard, S; Brunori, G; Camino Díaz, I; Cantizani, J; Carvalho, S; Castañeda Casado, P; Chatelain, E; Cotillo, I; Fiandor, JM; FRANCISCO, AF; Grimsditch, D; Keenan, M; KELLY, JM; Kessler, A; Luise, C; Lyon, JJ; MacLean, L; Marco, M; Martin, JJ; Martinez Martinez, MS; Paterson, C; Read, KD; ... De Rycker, M.
2023
Science translational medicine
Richard Wall

Contact

London School of Hygiene & Tropical Medicine
Keppel Street
London
WC1E 7HT
United Kingdom

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Related links

Centre for Global Health Discovery