The field evaluation study titled 鈥淒iagnostic performance of a novel loop-mediated isothermal amplification (LAMP) assay targeting the apicoplast genome for malaria diagnosis in a field setting in sub-Saharan Africa鈥 was recently published in Malaria Journal. A new molecular tool known as LAMP was optimised as part of Eniyou Oriero鈥檚 MRC funded PhD project to target a unique part of the plasmodium parasite that causes malaria.
The study which, was carried out in villages around the MRC Basse field station showed that the new LAMP test can detect very low amounts of malaria parasites present in healthy individuals than the commonly used methods (microscopy and rapid diagnostic test). This new tool can become useful for mass or focused screening and treatment campaigns, which are being proposed for use in countries that are considering elimination of malaria.
The first author of the publication, Dr Eniyou Oriero,a Postdoc Scientist, said 鈥渨e have come a long way from when molecular tools were a 鈥榤ystery鈥 in Africa and its routine use was only a dream. We now have the capacity not only to develop and evaluate these tools, but also to tailor them to meet our specific needs. In our efforts to fight disease in Africa we need to be more pro-active and the role of proper diagnosis cannot be overemphasized鈥.
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